The ‘Science, Technology, and National Innovation Ecosystem’, a horizontal research track at Pune International Centre (PIC) is dedicated to addressing complex national challenges through a purpose-driven, collaborative, and interdisciplinary approach and spans multiple research verticals and focus areas within PIC. Guided by the holistic STEP (Social, Technological, Economic, Policy) framework, the track focuses on leveraging science, technology, and innovation to enhance quality of life, foster economic growth, and deliver sustainable solutions. By engaging with like-minded organizations, experts, and stakeholders through discussions, workshops, and roundtables, STNIE drives impactful research and develops policy recommendations to advance national priorities and shape a better future.